FT2019-001: 2019-2020

Evaluation of IGF-2 in a rat model of AS. Primary Investigator: K. Nash Summary: The overall objective of the proposal is to evaluate whether insulin-like gr

FT2019-002: 2019-2020

ATFs 2.0: UBE3A activation without SNORD inhibition Primary Investigator: D. Segal Dr. Segal’s past work on Artificial transcription factors (ATFs) sho

FT2019-003: 2019-2020

Evaluation of IGF-2 and IGF-2 receptor ligand (L1) in a rat model of AS on the EEG and seizure phenotype Primary Investigator: A. Anderson Previous studies b

FT2019-004: 2019-2020

Evaluation of the rASO in the rad model of AS Primary Investigator: J. Silverman The objective of this grant is to evaluate the behavioral rescue in a rat mo

FT2019-005

Evaluation of rASO in a rat model of AS. Primary Investigator: K. Nash The use of ASOs to interrupt the paternal UBE3a allele silencing through antisense inh

FT2019-006: 2019-2020

Evaluation of the rASO in the rad model of AS on the EEG and seizure phenotype Primary Investigator: A. Anderson The objective of this grant is to evaluate w

FT2019-007: 2019-2021

Pilot feasibility of an enzyme replacement therapy for Angelman syndrome. Primary Investigator: D. Segal, J. Anderson A non-permanent treatment for genetic d

FT2019-008: 2019-2023

Translational Research in a Pig Model of Angelman Syndrome Primary Investigator: S. Dindot Dr. Scott Dindot is using an AS pig model to develop, test, and va

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